MAPK Phosphatase 7 Regulates T Cell Differentiation via Inhibiting ERK-Mediated IL-2 Expression

Members of the MAPK phosphatase (MKP) protein family play critical roles in immune responses through differential regulation of MAPK activation. In this study, we show that MKP7, also known as dual-specificity phosphatase 16, was required for CD4(+) T cell responses in vivo. Mkp7(−/−) CD4(+) T cells...

Full description

Saved in:
Bibliographic Details
Published in:J Immunol
Main Authors: Zhang, Yongliang, Nallaparaju, Kalyan C., Liu, Xin, Jiao, Huipeng, Reynolds, Joseph M., Wang, Zhi-Xin, Dong, Chen
Format: Artigo
Language:Inglês
Published: AAI 2015
Subjects:
Immune Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367158/
https://ncbi.nlm.nih.gov/pubmed/25716993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402638
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items