Mitogen-activated Protein Kinase (MAPK) Phosphatase 3-mediated Cross-talk between MAPKs ERK2 and p38α

MAPK phosphatase 3 (MKP3) is highly specific for ERK1/2 inactivation via dephosphorylation of both phosphotyrosine and phosphothreonine critical for enzymatic activation. Here, we show that MKP3 is able to effectively dephosphorylate the phosphotyrosine, but not phosphothreonine, in the activation l...

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Hlavní autoři: Zhang, Yuan-Yuan, Wu, Jia-Wei, Wang, Zhi-Xin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091224/
https://ncbi.nlm.nih.gov/pubmed/21454500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.203786
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