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Protease Allergens Induce the Expression of IL-25 via Erk and p38 MAPK Pathway

Allergic diseases, including asthma, are characterized by T helper type 2 (Th2) cell-mediated inflammations, coupled with tissue infiltration by eosinophils. In this study, we demonstrate that multiple protease allergens, including papain and DerP1, efficiently induce interleukin (IL)-25 and thymic...

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Detalhes bibliográficos
Main Authors: Yu, Hak Sun, Angkasekwinai, Pornpimon, Chang, Seon Hee, Chung, Yeonseok, Dong, Chen
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Academy of Medical Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877219/
https://ncbi.nlm.nih.gov/pubmed/20514301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3346/jkms.2010.25.6.829
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