Regulation of Adipose Tissue Inflammation and Insulin Resistance by MAPK Phosphatase 5

Obesity and metabolic disorders such as insulin resistance and type 2 diabetes have become a major threat to public health globally. The mechanisms that lead to insulin resistance in type 2 diabetes have not been well understood. In this study, we show that mice deficient in MAPK phosphatase 5 (MKP5...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Zhang, Yongliang, Nguyen, Thang, Tang, Peng, Kennedy, Norman J., Jiao, Huipeng, Zhang, Mingliang, Reynolds, Joseph M., Jaeschke, Anja, Martin-Orozco, Natalia, Chung, Yeonseok, He, Wei-min, Wang, Chen, Jia, Weiping, Ge, Baoxue, Davis, Roger J., Flavell, Richard A., Dong, Chen
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2015
Soggetti:
Metabolism
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463435/
https://ncbi.nlm.nih.gov/pubmed/25922079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.660969
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