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Inhibiting Protein Arginine Deiminases Has Antioxidant Consequences
Ulcerative colitis is a dynamic, idiopathic, chronic inflammatory condition that carries a high colon cancer risk. We previously showed that Cl-amidine, a small-molecule inhibitor of the protein arginine deiminases, suppresses colitis in mice. Because colitis is defined as inflammation of the colon...
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| Pubblicato in: | J Pharmacol Exp Ther |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society for Pharmacology and Experimental Therapeutics
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4366755/ https://ncbi.nlm.nih.gov/pubmed/25635139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.222745 |
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