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Insights into the Mechanism of Streptonigrin-Induced Protein Arginine Deiminase Inactivation

Protein citrullination is just one of more than 200 known PTMs. This modification, catalyzed by the Protein Arginine Deiminases (PADs 1–4 and PAD6 in humans), converts the positively charged guanidinium group of an arginine residue into a neutral ureido-group. Given the strong links between dysregul...

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Hlavní autoři: Dreyton, Christina J., Anderson, Erin D., Subramanian, Venkataraman, Boger, Dale L., Thompson, Paul R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954981/
https://ncbi.nlm.nih.gov/pubmed/24440480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.12.064
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