The Induction of microRNA-16 in Colon Cancer Cells by Protein Arginine Deiminase Inhibition Causes a p53-Dependent Cell Cycle Arrest

Protein Arginine Deiminases (PADs) catalyze the post-translational conversion of peptidyl-Arginine to peptidyl-Citrulline in a calcium-dependent, irreversible reaction. Evidence is emerging that PADs play a role in carcinogenesis. To determine the cancer-associated functional implications of PADs, w...

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Bibliografiske detaljer
Main Authors: Cui, Xiangli, Witalison, Erin E., Chumanevich, Alena P., Chumanevich, Alexander A., Poudyal, Deepak, Subramanian, Venkataraman, Schetter, Aaron J., Harris, Curtis C., Thompson, Paul R., Hofseth, Lorne J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538596/
https://ncbi.nlm.nih.gov/pubmed/23308284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053791
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