Genetic Analysis of TOR Complex Gene Variation With Human Longevity: A Nested Case–Control Study of American Men of Japanese Ancestry

The mechanistic target of rapamycin (mTOR) pathway is crucial for life span determination in model organisms. The aim of the present study was to test tagging single-nucleotide polymorphisms that captured most of the genetic variation across key TOR complex 1 (TORC1) and TOR complex 2 (TORC2) genes...

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Detaylı Bibliyografya
Yayımlandı:J Gerontol A Biol Sci Med Sci
Asıl Yazarlar: Morris, Brian J., Donlon, Timothy A., He, Qimei, Grove, John S., Masaki, Kamal H., Elliott, Ayako, Willcox, D. Craig, Allsopp, Richard, Willcox, Bradley J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2015
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366598/
https://ncbi.nlm.nih.gov/pubmed/24589862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glu021
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