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FOXO3 longevity interactome on chromosome 6

FOXO3 has been implicated in longevity in multiple populations. By DNA sequencing in long‐lived individuals, we identified all single nucleotide polymorphisms (SNPs) in FOXO3 and showed 41 were associated with longevity. Thirteen of these had predicted alterations in transcription factor binding sit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Aging Cell
Hauptverfasser: Donlon, Timothy A., Morris, Brian J., Chen, Randi, Masaki, Kamal H., Allsopp, Richard C., Willcox, D. Craig, Elliott, Ayako, Willcox, Bradley J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595686/
https://ncbi.nlm.nih.gov/pubmed/28722347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12625
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