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FOXO3 longevity interactome on chromosome 6

FOXO3 has been implicated in longevity in multiple populations. By DNA sequencing in long‐lived individuals, we identified all single nucleotide polymorphisms (SNPs) in FOXO3 and showed 41 were associated with longevity. Thirteen of these had predicted alterations in transcription factor binding sit...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Donlon, Timothy A., Morris, Brian J., Chen, Randi, Masaki, Kamal H., Allsopp, Richard C., Willcox, D. Craig, Elliott, Ayako, Willcox, Bradley J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595686/
https://ncbi.nlm.nih.gov/pubmed/28722347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12625
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