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Association of growth hormone receptor gene variant with longevity in men is due to amelioration of increased mortality risk from hypertension

The single nucleotide polymorphism (SNP) rs4130113 of the growth hormone receptor gene (GHR) is associated with longevity. Here we explored whether longevity-associated genotypes protect against mortality in all individuals, or only in individuals with aging-related diseases. Rs4130113 genotypes wer...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Aging (Albany NY)
Hauptverfasser: Donlon, Timothy A., Chen, Randi, Masaki, Kamal H., Willcox, D. Craig, Allsopp, Richard C., Willcox, Bradley J., Morris, Brian J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8221335/
https://ncbi.nlm.nih.gov/pubmed/34074802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.203133
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