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FOXO3 – A Major Gene for Human Longevity
BACKGROUND: The gene FOXO3, encoding the transcription factor forkhead box O-3 (FoxO3), is one of only two for which genetic polymorphisms have exhibited consistent associations with longevity in diverse human populations. OBJECTIVE: Here we review the multitude of actions of FoxO3 that are relevant...
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| Publicado no: | Gerontology |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5403515/ https://ncbi.nlm.nih.gov/pubmed/25832544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000375235 |
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