Genetic Analysis of TOR Complex Gene Variation With Human Longevity: A Nested Case–Control Study of American Men of Japanese Ancestry

The mechanistic target of rapamycin (mTOR) pathway is crucial for life span determination in model organisms. The aim of the present study was to test tagging single-nucleotide polymorphisms that captured most of the genetic variation across key TOR complex 1 (TORC1) and TOR complex 2 (TORC2) genes...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Gerontol A Biol Sci Med Sci
Prif Awduron: Morris, Brian J., Donlon, Timothy A., He, Qimei, Grove, John S., Masaki, Kamal H., Elliott, Ayako, Willcox, D. Craig, Allsopp, Richard, Willcox, Bradley J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2015
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366598/
https://ncbi.nlm.nih.gov/pubmed/24589862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glu021
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