Genetic Analysis of TOR Complex Gene Variation With Human Longevity: A Nested Case–Control Study of American Men of Japanese Ancestry

The mechanistic target of rapamycin (mTOR) pathway is crucial for life span determination in model organisms. The aim of the present study was to test tagging single-nucleotide polymorphisms that captured most of the genetic variation across key TOR complex 1 (TORC1) and TOR complex 2 (TORC2) genes...

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Dades bibliogràfiques
Publicat a:J Gerontol A Biol Sci Med Sci
Autors principals: Morris, Brian J., Donlon, Timothy A., He, Qimei, Grove, John S., Masaki, Kamal H., Elliott, Ayako, Willcox, D. Craig, Allsopp, Richard, Willcox, Bradley J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366598/
https://ncbi.nlm.nih.gov/pubmed/24589862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glu021
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