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Genetic Analysis of TOR Complex Gene Variation With Human Longevity: A Nested Case–Control Study of American Men of Japanese Ancestry
The mechanistic target of rapamycin (mTOR) pathway is crucial for life span determination in model organisms. The aim of the present study was to test tagging single-nucleotide polymorphisms that captured most of the genetic variation across key TOR complex 1 (TORC1) and TOR complex 2 (TORC2) genes...
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| Veröffentlicht in: | J Gerontol A Biol Sci Med Sci |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4366598/ https://ncbi.nlm.nih.gov/pubmed/24589862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glu021 |
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