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Genetic Analysis of TOR Complex Gene Variation With Human Longevity: A Nested Case–Control Study of American Men of Japanese Ancestry

The mechanistic target of rapamycin (mTOR) pathway is crucial for life span determination in model organisms. The aim of the present study was to test tagging single-nucleotide polymorphisms that captured most of the genetic variation across key TOR complex 1 (TORC1) and TOR complex 2 (TORC2) genes...

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Bibliographische Detailangaben
Veröffentlicht in:J Gerontol A Biol Sci Med Sci
Hauptverfasser: Morris, Brian J., Donlon, Timothy A., He, Qimei, Grove, John S., Masaki, Kamal H., Elliott, Ayako, Willcox, D. Craig, Allsopp, Richard, Willcox, Bradley J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366598/
https://ncbi.nlm.nih.gov/pubmed/24589862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glu021
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