Isoglutaminyl cyclase contributes to CCL2-driven neuroinflammation in Alzheimer’s disease

The brains of Alzheimer’s disease (AD) patients are characterized by deposits of Abeta peptides and by accompanying chronic inflammation. Here, we provide evidence that the enzyme isoglutaminyl cyclase (isoQC) is a novel factor contributing to both aspects of AD pathology. Two putative substrates of...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Acta Neuropathol
Asıl Yazarlar: Hartlage-Rübsamen, Maike, Waniek, Alexander, Meißner, Juliane, Morawski, Markus, Schilling, Stephan, Jäger, Carsten, Kleinschmidt, Martin, Cynis, Holger, Kehlen, Astrid, Arendt, Thomas, Demuth, Hans-Ulrich, Roßner, Steffen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer Berlin Heidelberg 2015
Konular:
Original Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366547/
https://ncbi.nlm.nih.gov/pubmed/25666182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-015-1395-2
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller