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Sensitization of nociceptive spinal neurons contributes to pain in a transgenic model of sickle cell disease

Chronic pain is a major characteristic feature of sickle cell disease (SCD). The refractory nature of pain and the development of chronic pain syndromes in many patients with SCD suggest that central neural mechanisms contribute to pain in this disease. We used HbSS-BERK sickle mice, which show chro...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Pain
मुख्य लेखकों: Cataldo, Giuseppe, Rajput, Sugandha, Gupta, Kalpna, Simone, Donald A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366346/
https://ncbi.nlm.nih.gov/pubmed/25630029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000000104
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