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Sensitization of nociceptive spinal neurons contributes to pain in a transgenic model of sickle cell disease
Chronic pain is a major characteristic feature of sickle cell disease (SCD). The refractory nature of pain and the development of chronic pain syndromes in many patients with SCD suggest that central neural mechanisms contribute to pain in this disease. We used HbSS-BERK sickle mice, which show chro...
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| Publicado no: | Pain |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4366346/ https://ncbi.nlm.nih.gov/pubmed/25630029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000000104 |
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