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Dissecting the contribution of knee joint NGF to spinal nociceptive sensitization in a model of OA pain in the rat

OBJECTIVE: Although analgesic approaches targeting nerve growth factor (NGF) for the treatment of osteoarthritis (OA) pain remain of clinical interest, neurophysiological mechanisms by which NGF contribute to OA pain remain unclear. We investigated the impact of local elevation of knee joint NGF on...

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Detalhes bibliográficos
Publicado no:Osteoarthritis Cartilage
Main Authors: Sagar, D.R., Nwosu, L., Walsh, D.A., Chapman, V.
Formato: Artigo
Idioma:Inglês
Publicado em: W.B. Saunders For The Osteoarthritis Research Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459966/
https://ncbi.nlm.nih.gov/pubmed/25623624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2015.01.010
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