Probenecid as a Noninjurious Positive Inotrope in an Ischemic Heart Disease Murine Model

The current therapeutic options for acute decompensated heart failure are limited to afterload reducers and positive inotropes. The latter increases myocardial contractility through changes in myocyte calcium (Ca(2+)) handling (mostly through stimulation of the β-adrenergic pathways [β-ADR]) and is...

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Gepubliceerd in:J Cardiovasc Pharmacol Ther
Hoofdauteurs: Koch, Sheryl E., Tranter, Michael, Robbins, Nathan, Luther, Kristin, Singh, Umesh, Jiang, Min, Ren, Xiaoping, Tee, Trisha, Smith, Leah, Varma, Priyanka, Jones, W. Keith, Rubinstein, Jack
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365873/
https://ncbi.nlm.nih.gov/pubmed/23241275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1074248412469299
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