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Probenecid treatment improves outcomes in a novel mouse model of peripartum cardiomyopathy

Probenecid has been used for decades in the treatment of gout but recently has also been found to improve outcomes in patients with heart failure via stimulation of the transient receptor potential vanilloid 2 (TRPV2) channel in cardiomyocytes. This study tested the use of probenecid on a novel mous...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Onusko, Evan, McDermott, Michael R., Robbins, Nathan, Liu, Guansheng, Kranias, Evangelia G., Rubinstein, Jack, Koch, Sheryl E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7100971/
https://ncbi.nlm.nih.gov/pubmed/32218573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0230386
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