Probenecid as a Noninjurious Positive Inotrope in an Ischemic Heart Disease Murine Model

The current therapeutic options for acute decompensated heart failure are limited to afterload reducers and positive inotropes. The latter increases myocardial contractility through changes in myocyte calcium (Ca(2+)) handling (mostly through stimulation of the β-adrenergic pathways [β-ADR]) and is...

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Detalhes bibliográficos
Publicado no:J Cardiovasc Pharmacol Ther
Main Authors: Koch, Sheryl E., Tranter, Michael, Robbins, Nathan, Luther, Kristin, Singh, Umesh, Jiang, Min, Ren, Xiaoping, Tee, Trisha, Smith, Leah, Varma, Priyanka, Jones, W. Keith, Rubinstein, Jack
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365873/
https://ncbi.nlm.nih.gov/pubmed/23241275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1074248412469299
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