Probenecid as a Noninjurious Positive Inotrope in an Ischemic Heart Disease Murine Model

The current therapeutic options for acute decompensated heart failure are limited to afterload reducers and positive inotropes. The latter increases myocardial contractility through changes in myocyte calcium (Ca(2+)) handling (mostly through stimulation of the β-adrenergic pathways [β-ADR]) and is...

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Publicat a:J Cardiovasc Pharmacol Ther
Autors principals: Koch, Sheryl E., Tranter, Michael, Robbins, Nathan, Luther, Kristin, Singh, Umesh, Jiang, Min, Ren, Xiaoping, Tee, Trisha, Smith, Leah, Varma, Priyanka, Jones, W. Keith, Rubinstein, Jack
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365873/
https://ncbi.nlm.nih.gov/pubmed/23241275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1074248412469299
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