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FoxO-BNIP3 axis exerts a unique regulation of mTORC1 and cell survival under energy stress
Normal cells possess adaptive mechanisms to couple energy availability with cell growth (cell size increase) and survival, and imbalances are associated with major diseases such as cancer. Inactivation of critical regulators involved in energy stress response, including AMPK, LKB1, TSC1, and TSC2, l...
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| Publicado no: | Oncogene |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4365448/ https://ncbi.nlm.nih.gov/pubmed/23851496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.273 |
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