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Testosterone regulation of Akt/mTORC1/FoxO3a Signaling in Skeletal Muscle

Low endogenous testosterone production, known as hypogonadism is commonly associated with conditions inducing muscle wasting. Akt signaling can control skeletal muscle mass through mTOR regulation of protein synthesis and FoxO regulation of protein degradation, and this pathway has been previously i...

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Detalhes bibliográficos
Main Authors: White, James P., Gao, Song, Puppa, Melissa J., Sato, Shuichi, Welle, Stephen L., Carson, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529800/
https://ncbi.nlm.nih.gov/pubmed/23116773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2012.10.019
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