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Testosterone regulation of Akt/mTORC1/FoxO3a Signaling in Skeletal Muscle

Low endogenous testosterone production, known as hypogonadism is commonly associated with conditions inducing muscle wasting. Akt signaling can control skeletal muscle mass through mTOR regulation of protein synthesis and FoxO regulation of protein degradation, and this pathway has been previously i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: White, James P., Gao, Song, Puppa, Melissa J., Sato, Shuichi, Welle, Stephen L., Carson, James A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529800/
https://ncbi.nlm.nih.gov/pubmed/23116773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2012.10.019
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