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Muscle mTORC1 suppression by IL-6 during cancer cachexia: a role for AMPK
Although catabolic signaling has a well-established role in muscle wasting during cancer cachexia, the suppression of anabolic signaling also warrants further investigation. In cachectic tumor-bearing mice, circulating IL-6 levels are associated with suppressed muscle protein synthesis and mTORC1 si...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3651620/ https://ncbi.nlm.nih.gov/pubmed/23531613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00410.2012 |
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