SNP genotyping using TaqMan® technology: the CYP2D6*17 assay conundrum

CYP2D6 contributes to the metabolism of many clinically used drugs and is increasingly tested to individualize drug therapy. The CYP2D6 gene is challenging to genotype due to the highly complex nature of its gene locus. TaqMan® technology is widely used in the clinical and research settings for geno...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gaedigk, Andrea, Freeman, Natalie, Hartshorne, Toinette, Riffel, Amanda K., Irwin, David, Bishop, Jeffrey R., Stein, Mark A., Newcorn, Jeffrey H., Jaime, Lazara Karelia Montané, Cherner, Mariana, Leeder, J. Steven
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365394/
https://ncbi.nlm.nih.gov/pubmed/25788121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09257
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