SNP genotyping using TaqMan® technology: the CYP2D6*17 assay conundrum

CYP2D6 contributes to the metabolism of many clinically used drugs and is increasingly tested to individualize drug therapy. The CYP2D6 gene is challenging to genotype due to the highly complex nature of its gene locus. TaqMan® technology is widely used in the clinical and research settings for geno...

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Vydáno v:Sci Rep
Hlavní autoři: Gaedigk, Andrea, Freeman, Natalie, Hartshorne, Toinette, Riffel, Amanda K., Irwin, David, Bishop, Jeffrey R., Stein, Mark A., Newcorn, Jeffrey H., Jaime, Lazara Karelia Montané, Cherner, Mariana, Leeder, J. Steven
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365394/
https://ncbi.nlm.nih.gov/pubmed/25788121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09257
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