IMD-4690, a Novel Specific Inhibitor for Plasminogen Activator Inhibitor-1, Reduces Allergic Airway Remodeling in a Mouse Model of Chronic Asthma via Regulating Angiogenesis and Remodeling-Related Mediators

Plasminogen activator inhibitor (PAI)-1 is the principal inhibitor of plasminogen activators, and is responsible for the degradation of fibrin and extracellular matrix. IMD-4690 is a newly synthesized inhibitor for PAI-1, whereas the effect on allergic airway inflammation and remodeling is still unc...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Tezuka, Toshifumi, Ogawa, Hirohisa, Azuma, Masahiko, Goto, Hisatsugu, Uehara, Hisanori, Aono, Yoshinori, Hanibuchi, Masaki, Yamaguchi, Yoichi, Fujikawa, Tomoyuki, Itai, Akiko, Nishioka, Yasuhiko
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364779/
https://ncbi.nlm.nih.gov/pubmed/25785861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121615
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items