Paediatric leukaemia DNA methylation profiling using MBD enrichment and SOLiD sequencing on archival bone marrow smears

BACKGROUND: Acute Lymphoblastic Leukaemia (ALL) is the most common cancer in children. Over the past four decades, research has advanced the treatment of this cancer from a less than 60% chance of survival to over 85% today. The causal molecular mechanisms remain unclear. Here, we performed sequenci...

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Publicat a:Gigascience
Autors principals: Wong, Nicholas CL, Meredith, Gavin D, Marnellos, George, Dudas, Miroslav, Parkinson-Bates, Mandy, Halemba, Minhee Suh, Chatterton, Zac, Maksimovic, Jovana, Ashley, David M, Mechinaud, Francoise, Craig, Jeffrey M, Saffery, Richard
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
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Data Note
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364676/
https://ncbi.nlm.nih.gov/pubmed/25789165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13742-015-0050-0
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