High Resolution Detection and Analysis of CpG Dinucleotides Methylation Using MBD-Seq Technology

Methyl-CpG binding domain protein sequencing (MBD-seq) is widely used to survey DNA methylation patterns. However, the optimal experimental parameters for MBD-seq remain unclear and the data analysis remains challenging. In this study, we generated high depth MBD-seq data in MCF-7 cell and developed...

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Detalhes bibliográficos
Main Authors: Lan, Xun, Adams, Christopher, Landers, Mark, Dudas, Miroslav, Krissinger, Daniel, Marnellos, George, Bonneville, Russell, Xu, Maoxiong, Wang, Junbai, Huang, Tim H.-M., Meredith, Gavin, Jin, Victor X.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136941/
https://ncbi.nlm.nih.gov/pubmed/21779396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022226
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