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Increased G + C content of DNA stabilizes methyl CpG dinucleotides.
The vertebrate genome is a mosaic of regions differing dramatically in their G + C content. Those regions with a high G + C content contain the expected number of CpG dinucleotides and we propose that following methylation these have been protected from deamination by the increased stability of the...
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| Main Authors: | , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1984
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC320037/ https://ncbi.nlm.nih.gov/pubmed/6462920 |
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