The effects of O6-methyl guanine DNA-methyl transferase promotor methylation and CpG1, CpG2, CpG3 and CpG4 methylation on treatment response and their prognostic significance in patients with glioblastoma

This retrospective study examined the prognostic significance and treatment effect of promoter methylation of O6- methyl guanine methyl transferase (MGMT) and meth-ylation of CpG 1, CpG2, CpG3 and CpG4 in glioblastoma (GB) patients received postoperative radiotherapy (PORT), with or without adjuvant...

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Detalhes bibliográficos

Principais autores:	Yildiz OG, Aslan D, Akalin H, Erdem Y, Canoz O, Aytekin A, Ozoner S, Dundar M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Sciendo 2020-08-01
coleção:	Balkan Journal of Medical Genetics
Assuntos:	glioblastoma (gb) o6-methyl guanine methyl transferase (mgmt) methylation radiotherapy (rt)
Acesso em linha:	https://doi.org/10.2478/bjmg-2020-0015
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