Screening significantly hypermethylated genes in fetal tissues compared with maternal blood using a methylated-CpG island recovery assay-based microarray

<p>Abstract</p> <p>Background</p> <p>The noninvasive prenatal diagnosis procedures that are currently used to detect genetic diseases do not achieve desirable levels of sensitivity and specificity. Recently, fetal methylated DNA biomarkers in maternal peripheral blood have been explored for the noni...

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Bibliografiske detaljer

Principais autores:	Yin Aihua, Zhang Xiangzhong, Wu Jing, Du Li, He Tianwen, Zhang Xiaozhuang
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMC 2012-06-01
Serier:	BMC Medical Genomics
Fag:	CpG islands methylation Methyl-CpG binding protein Microarray Combined bisulfite restriction analysis
Online adgang:	http://www.biomedcentral.com/1755-8794/5/26
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