Increased G + C content of DNA stabilizes methyl CpG dinucleotides.
The vertebrate genome is a mosaic of regions differing dramatically in their G + C content. Those regions with a high G + C content contain the expected number of CpG dinucleotides and we propose that following methylation these have been protected from deamination by the increased stability of the...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1984
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC320037/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6462920/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/12.14.5869 |
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