DNA methylation and the frequency of CpG in animal DNA.
An analysis of nearest neighbour dinucleotide frequencies and the level of DNA methylation in animals strongly supports the suggestion that 5-methylcytosine (5mC) tends to mutate abnormally frequently to T. This tendency is the likely cause of the CpG deficiency in heavily methylated genomes.
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| Veröffentlicht in: | Nucleic Acids Res |
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| 1. Verfasser: | |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1980
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC324012/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6253938/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/8.7.1499 |
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