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DNA methylation and the frequency of CpG in animal DNA.

An analysis of nearest neighbour dinucleotide frequencies and the level of DNA methylation in animals strongly supports the suggestion that 5-methylcytosine (5mC) tends to mutate abnormally frequently to T. This tendency is the likely cause of the CpG deficiency in heavily methylated genomes.

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Detalhes bibliográficos
Autor principal: Bird, A P
Formato: Artigo
Idioma:Inglês
Publicado em: 1980
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC324012/
https://ncbi.nlm.nih.gov/pubmed/6253938
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