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An alignment algorithm for bisulfite sequencing using the Applied Biosystems SOLiD System

Summary: Bisulfite sequencing allows cytosine methylation, an important epigenetic marker, to be detected via nucleotide substitutions. Since the Applied Biosystems SOLiD System uses a unique di-base encoding that increases confidence in the detection of nucleotide substitutions, it is a potentially...

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Detalhes bibliográficos
Main Authors: Ondov, Brian D., Cochran, Charles, Landers, Mark, Meredith, Gavin D., Dudas, Miroslav, Bergman, Nicholas H.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905549/
https://ncbi.nlm.nih.gov/pubmed/20562417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq291
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