Hypermethylation and down-regulation of DLEU2 in paediatric acute myeloid leukaemia independent of embedded tumour suppressor miR-15a/16-1

BACKGROUND: Acute Myeloid Leukaemia (AML) is a highly heterogeneous disease. Studies in adult AML have identified epigenetic changes, specifically DNA methylation, associated with leukaemia subtype, age of onset and patient survival which highlights this heterogeneity. However, only limited DNA meth...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Morenos, Leah, Chatterton, Zac, Ng, Jane L, Halemba, Minhee S, Parkinson-Bates, Mandy, Mechinaud, Francoise, Elwood, Ngaire, Saffery, Richard, Wong, Nicholas C
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050407/
https://ncbi.nlm.nih.gov/pubmed/24885794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-123
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki