Hypermethylation and down-regulation of DLEU2 in paediatric acute myeloid leukaemia independent of embedded tumour suppressor miR-15a/16-1

BACKGROUND: Acute Myeloid Leukaemia (AML) is a highly heterogeneous disease. Studies in adult AML have identified epigenetic changes, specifically DNA methylation, associated with leukaemia subtype, age of onset and patient survival which highlights this heterogeneity. However, only limited DNA meth...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Morenos, Leah, Chatterton, Zac, Ng, Jane L, Halemba, Minhee S, Parkinson-Bates, Mandy, Mechinaud, Francoise, Elwood, Ngaire, Saffery, Richard, Wong, Nicholas C
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050407/
https://ncbi.nlm.nih.gov/pubmed/24885794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-123
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky