Hypermethylation and down-regulation of DLEU2 in paediatric acute myeloid leukaemia independent of embedded tumour suppressor miR-15a/16-1

BACKGROUND: Acute Myeloid Leukaemia (AML) is a highly heterogeneous disease. Studies in adult AML have identified epigenetic changes, specifically DNA methylation, associated with leukaemia subtype, age of onset and patient survival which highlights this heterogeneity. However, only limited DNA meth...

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Detaylı Bibliyografya
Asıl Yazarlar: Morenos, Leah, Chatterton, Zac, Ng, Jane L, Halemba, Minhee S, Parkinson-Bates, Mandy, Mechinaud, Francoise, Elwood, Ngaire, Saffery, Richard, Wong, Nicholas C
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2014
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050407/
https://ncbi.nlm.nih.gov/pubmed/24885794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-123
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