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Brca2 Deficiency Leads to T Cell Loss and Immune Dysfunction
Germline mutations in the breast cancer type 2 susceptibility gene (BRCA2) are linked to familial breast cancer and the progressive bone marrow failure syndrome Fanconi anaemia. Established Brca2 mouse knockout models show embryonic lethality, but those with a truncating mutation at the C-terminus s...
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| Publicado no: | Mol Cells |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Korean Society for Molecular and Cellular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4363725/ https://ncbi.nlm.nih.gov/pubmed/25666348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2015.2302 |
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