Loss of BRCA1 leads to an increased sensitivity to Bisphenol A

Humans are chronically exposed to the plasticizer, Bisphenol A (BPA) that can adversely affect the normal hormonal regulation of cellular functions by mimicking the actions of estrogen. This biological response to BPA may vary according to an individual’s genetic characteristics (e.g., BRCA1 mutatio...

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Detalhes bibliográficos
Main Authors: Jones, Laundette P., Sampson, Aishia, Kang, Hyo Jin, Kim, Hee Jeong, Yi, Yong-Weon, Kwon, Sun Young, Babus, Janice K., Wang, Antai, Bae, Insoo
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505996/
https://ncbi.nlm.nih.gov/pubmed/20868731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2010.09.008
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