Loss of BRCA1 leads to an increased sensitivity to Bisphenol A

Humans are chronically exposed to the plasticizer, Bisphenol A (BPA) that can adversely affect the normal hormonal regulation of cellular functions by mimicking the actions of estrogen. This biological response to BPA may vary according to an individual’s genetic characteristics (e.g., BRCA1 mutatio...

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Main Authors: Jones, Laundette P., Sampson, Aishia, Kang, Hyo Jin, Kim, Hee Jeong, Yi, Yong-Weon, Kwon, Sun Young, Babus, Janice K., Wang, Antai, Bae, Insoo
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505996/
https://ncbi.nlm.nih.gov/pubmed/20868731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2010.09.008
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