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Bioactive food components prevent carcinogenic stress via Nrf2 activation in BRCA1 deficient breast epithelial cells

Although BRCA1 is the most prevalent genetic factor in breast cancer, the pathologic mechanism of tumorigenesis caused by its deficiency has not been elucidated. We have previously demonstrated that BRCA1 can modulate responses to xenobiotic stress by regulating expression of genes involved in metab...

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Autors principals: Kang, Hyo Jin, Hong, Young Bin, Kim, Hee Jeong, Wang, Antai, Bae, Insoo
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508677/
https://ncbi.nlm.nih.gov/pubmed/22192953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2011.12.002
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