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Bioactive food components prevent carcinogenic stress via Nrf2 activation in BRCA1 deficient breast epithelial cells

Although BRCA1 is the most prevalent genetic factor in breast cancer, the pathologic mechanism of tumorigenesis caused by its deficiency has not been elucidated. We have previously demonstrated that BRCA1 can modulate responses to xenobiotic stress by regulating expression of genes involved in metab...

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Detalhes bibliográficos
Main Authors: Kang, Hyo Jin, Hong, Young Bin, Kim, Hee Jeong, Wang, Antai, Bae, Insoo
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508677/
https://ncbi.nlm.nih.gov/pubmed/22192953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2011.12.002
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