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Development of thymic lymphomas in mice disrupted of Brca2 allele in the thymus
Germ-line mutations in BRCA2 predispose to early-onset cancer. Homozygous mutant mouse, which has Brca2 truncated in exon 11 exhibit paradoxic occurrence of growth retardation and development of thymic lymphomas. However, due to its large embryonic lethality, cohort studies on the thymic lymphomas w...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Korean Society of Medical Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2679290/ https://ncbi.nlm.nih.gov/pubmed/18587272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2008.40.3.339 |
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