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Binding of Complement Factor H to PorB3 and NspA Enhances Resistance of Neisseria meningitidis to Anti-Factor H Binding Protein Bactericidal Activity

Among 25 serogroup B Neisseria meningitidis clinical isolates, we identified four (16%) with high factor H binding protein (FHbp) expression that were resistant to complement-mediated bactericidal activity of sera from mice immunized with recombinant FHbp vaccines. Two of the four isolates had evide...

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Bibliografiset tiedot
Julkaisussa:Infect Immun
Päätekijät: Giuntini, Serena, Pajon, Rolando, Ram, Sanjay, Granoff, Dan M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363443/
https://ncbi.nlm.nih.gov/pubmed/25644002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02984-14
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