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A homopolymeric adenosine tract in the promoter region of nspA influences factor H-mediated serum resistance in Neisseria meningitidis

Although usually asymptomatically colonizing the human nasopharynx, the Gram-negative bacterium Neisseria meningitidis (meningococcus) can spread to the blood stream and cause invasive disease. For survival in blood, N. meningitidis evades the complement system by expression of a polysaccharide caps...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Claus, Heike, Hubert, Kerstin, Becher, Dörte, Otto, Andreas, Pawlik, Marie-Christin, Lappann, Ines, Strobel, Lea, Vogel, Ulrich, Johswich, Kay
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6389960/
https://ncbi.nlm.nih.gov/pubmed/30804422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39231-0
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