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Insulin Receptor Signaling in the GnRH Neuron Plays a Role in the Abnormal GnRH Pulsatility of Obese Female Mice

Infertility associated with obesity is characterized by abnormal hormone release from reproductive tissues in the hypothalamus, pituitary, and ovary. These tissues maintain insulin sensitivity upon peripheral insulin resistance. Insulin receptor signaling may play a role in the dysregulation of gona...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: DiVall, Sara A., Herrera, Danny, Sklar, Bonnie, Wu, Sheng, Wondisford, Fredric, Radovick, Sally, Wolfe, Andrew
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363364/
https://ncbi.nlm.nih.gov/pubmed/25780937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119995
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