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Insulin Receptor Signaling in the GnRH Neuron Plays a Role in the Abnormal GnRH Pulsatility of Obese Female Mice

Infertility associated with obesity is characterized by abnormal hormone release from reproductive tissues in the hypothalamus, pituitary, and ovary. These tissues maintain insulin sensitivity upon peripheral insulin resistance. Insulin receptor signaling may play a role in the dysregulation of gona...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: DiVall, Sara A., Herrera, Danny, Sklar, Bonnie, Wu, Sheng, Wondisford, Fredric, Radovick, Sally, Wolfe, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363364/
https://ncbi.nlm.nih.gov/pubmed/25780937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119995
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