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Insulin augments GnRH-stimulated LHβ gene expression by Egr-1
Previous studies have shown that insulin augments GnRH-stimulated LH synthesis and release from primary gonadotrophs. In this study, regulation of LHβ gene expression by GnRH and insulin was examined in LβT2 cells. Endogenous LHβ mRNA is stimulated 2.4-fold by insulin alone, 2.6-fold by GnRH alone,...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3464308/ https://ncbi.nlm.nih.gov/pubmed/16530935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2006.02.001 |
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