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Egr-1 Binds the GnRH Promoter to Mediate the Increase in Gene Expression by Insulin

Insulin increases gonadotropin- releasing hormone (GnRH) gene expression in in vitro models of GnRH neurons. Early growth response-1 (Egr-1) is a transcription factor that mediates the effect of insulin on target genes. In the GN11 cell line—an immortalized GnRH-secreting neuronal cell line—insulin...

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Bibliografiska uppgifter
Huvudupphovsmän: DiVall, Sara A., Radovick, Sally, Wolfe, Andrew
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976257/
https://ncbi.nlm.nih.gov/pubmed/17379398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2007.02.007
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