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Egr-1 Binds the GnRH Promoter to Mediate the Increase in Gene Expression by Insulin
Insulin increases gonadotropin- releasing hormone (GnRH) gene expression in in vitro models of GnRH neurons. Early growth response-1 (Egr-1) is a transcription factor that mediates the effect of insulin on target genes. In the GN11 cell line—an immortalized GnRH-secreting neuronal cell line—insulin...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1976257/ https://ncbi.nlm.nih.gov/pubmed/17379398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2007.02.007 |
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