Divergent roles of growth factors in the GnRH regulation of puberty in mice

Pubertal onset, initiated by pulsatile gonadotropin-releasing hormone (GnRH), only occurs in a favorable, anabolic hormonal milieu. Anabolic factors that may signal nutritional status to the hypothalamus include the growth factors insulin and IGF-1. It is unclear which hypothalamic neuronal subpopul...

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Detalhes bibliográficos
Main Authors: DiVall, Sara A., Williams, Tameeka R., Carver, Sarah E., Koch, Linda, Brüning, Jens C., Kahn, C. Ronald, Wondisford, Fredric, Radovick, Sally, Wolfe, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912185/
https://ncbi.nlm.nih.gov/pubmed/20628204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI41069
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